Degenerate Oligonucleotide-Primed PCR (DOPPCR): Evaluation of its Reliability for Screening of Genetic Alterations in Neoplasia
نویسندگان
چکیده
منابع مشابه
Degenerate oligonucleotide-primed PCR (DOP-PCR): evaluation of its reliability for screening of genetic alterations in neoplasia.
Genetic alterations underlie the development and progression of neoplasia. Screening for genetic alterations in biopsies and premalignant lesions, where the neoplastic tissue analyzed usually constitutes only a small fraction of the cells in the specimen, often is difficult and tedious. Even after successful isolation of DNA, limited quantities allow only a few genetic analyses, limiting the id...
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ژورنال
عنوان ژورنال: BioTechniques
سال: 1998
ISSN: 0736-6205,1940-9818
DOI: 10.2144/98256cr01